Bitopertin
Product Specifications
CAS Number
845614-11-1
Synonyms
RG1678, RO-4917838
Target
GlyT
Applications
Neuronal Signaling
Smiles
CC (C (F) (F) F) OC1=C (C=C (C=C1) S (=O) (=O) C) C (=O) N2CCN (CC2) C3=C (C=C (C=N3) C (F) (F) F) F
Molecular Formula
C21H20F7N3O4S
Additionnal Information
Bitopertin (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.
Storage Conditions
2 years -80 in solvent
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