NSC87877
Product Specifications
CAS Number
56932-43-5
Target
Phosphatase
Applications
Metabolism
Smiles
C1=CC2=C (C=C (C (=C2N=C1) O) N=NC3=CC4=C (C=C3) C=C (C=C4) S (=O) (=O) [O-]) S (=O) (=O) [O-].[Na+].[Na+]
Molecular Formula
C19H13N3O7S2.2Na
Additionnal Information
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Storage Conditions
2 years -80 in solvent
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