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Voruciclib

Product Specifications

CAS Number

1000023-04-0

Synonyms

P1446A-05

Target

CDK

Applications

Cell Cycle

Molecular Formula

C22H19ClF3NO5

Additionnal Information

Voruciclib (P1446A-05) is a small molecule flavone derivative, a pan inhibitor of CDK with Ki's of 0.626 nM-9.1nM, that potently targets CDK9, represses expression of MCL-1 and leads to tumor cell apoptosis and tumor growth inhibition in multiple models of diffuse large B-cell lymphoma (DLBCL) .

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