Paxalisib (GDC-0084)
Product Specifications
CAS Number
1382979-44-3
Synonyms
RG7666
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CC1 (C2=NC3=C (N2CCO1) N=C (N=C3N4CCOCC4) C5=CN=C (N=C5) N) C
Molecular Formula
C18H22N8O2
Additionnal Information
Paxalisib (GDC-0084, RG7666) is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: OTI18E8]](https://cdn.genprice.uk/products/937/68dd18b9061270361e9081d0/imageurl/cf807862.webp)
CF807862 100 µg
PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: OTI18E8]
Sign In for Pricing
View Details 
TP305846L 1 mg
splicing factor 1 (SF1) (NM_201998) Human Recombinant Protein
Sign In for Pricing
View Details 
BNC682044-100 1x 100 µL
TIMP2 (Tissue Inhibitor of Metalloproteinase 2) (TIMP2/2044), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 