Upadacitinib
Product Specifications
CAS Number
1310726-60-3
Synonyms
ABT-494
Target
JAK
Applications
Angiogenesis
Smiles
CCC1CN (CC1C2=CN=C3N2C4=C (NC=C4) N=C3) C (=O) NCC (F) (F) F
Molecular Formula
C17H19F3N6O
Additionnal Information
Upadacitinib is a selective JAK1 inhibitor which demonstrates activity against JAK1 (0.045 μM) and JAK2 (0.109 μM), with > 40 fold selectivity over JAK3 (2.1 μM) and 100 fold selectivity over TYK2 (4.7 μM) as compared to JAK1.
Storage Conditions
3 years -20°C powder
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