ARS-853
Product Specifications
CAS Number
1629268-00-3
Target
Ras
Applications
Apoptosis
Smiles
CC1 (CC1) C2=CC (=C (C=C2Cl) O) NCC (=O) N3CCN (CC3) C4CN (C4) C (=O) C=C
Molecular Formula
C22H29ClN4O3
Additionnal Information
ARS-853 is a selective, covalent KRAS (G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation. ARS-853 also induces apoptosis.
Storage Conditions
2 years -80 in solvent
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