PD0166285
Product Specifications
CAS Number
185039-89-8
Target
Wee1
Applications
Cell Cycle
Smiles
CCN (CC) CCOC1=CC=C (C=C1) NC2=NC=C3C=C (C (=O) N (C3=N2) C) C4=C (C=CC=C4Cl) Cl
Molecular Formula
C26H27Cl2N5O2
Additionnal Information
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1) . PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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