Cl-amidine

Product Specifications

CAS Number

1043444-18-3

Target

Immunology & Inflammation related

Applications

Immunology & Inflammation

Smiles

C1=CC=C (C=C1) C (=O) NC (CCCN=C (CCl) N) C (=O) N.C (=O) (C (F) (F) F) O

Molecular Formula

C14H19ClN4O2.C2HF3O2

Additionnal Information

Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.

Storage Conditions

2 years -80 in solvent

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