Cl-amidine
Product Specifications
CAS Number
1043444-18-3
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Smiles
C1=CC=C (C=C1) C (=O) NC (CCCN=C (CCl) N) C (=O) N.C (=O) (C (F) (F) F) O
Molecular Formula
C14H19ClN4O2.C2HF3O2
Additionnal Information
Cl-amidine is an irreversible pan-peptidylarginine deiminase (PAD) inhibitor with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. Cl-amidine induces apoptosis.
Storage Conditions
2 years -80 in solvent
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