GNF-7
Product Specifications
CAS Number
839706-07-9
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) NC (=O) C2=CC (=CC=C2) C (F) (F) F) N3CC4=CN=C (N=C4N (C3=O) C) NC5=CN=C (C=C5) C
Molecular Formula
C28H24F3N7O2
Additionnal Information
GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.
Storage Conditions
2 years -80 in solvent
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