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GMX1778

Product Specifications

CAS Number

200484-11-3

Synonyms

CHS828

Target

NAMPT

Applications

Metabolism

Smiles

C1=CC (=CC=C1OCCCCCCN=C (NC#N) NC2=CC=NC=C2) Cl

Molecular Formula

C19H22ClN5O

Additionnal Information

GMX1778 is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and Kd of < 25 nM and 120 nM, respectively. GMX1778 induces programmed cell death with apoptotic features. Phase 1.

Storage Conditions

2 years -80 in solvent

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