What is the catalog number for GANT61?

The catalog number for GANT61 is C13174-10mg.

What sizes are available for GANT61?

GANT61 is available in the following size(s): 10 mg.

GANT61 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for GANT61?

GANT61 is requires dry ice shipping.

GANT61

Product Specifications

CAS Number

500579-04-4

Synonyms

NSC 136476

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

CN (C) C1=CC=CC=C1CN2CCCN (C2C3=CC=NC=C3) CC4=CC=CC=C4N (C) C

Molecular Formula

C27H35N5

Additionnal Information

GANT61 (NSC 136476) is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM in GLI1 expressing HEK293T cell, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation. GANT61 induces apoptosis and activates protective autophagy in LX-2 cells.