Chaetocin
Product Specifications
CAS Number
28097-03-2
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CN1C (=O) C23CC4 (C (N2C (=O) C1 (SS3) CO) NC5=CC=CC=C54) C67CC89C (=O) N (C (C (=O) N8C6NC1=CC=CC=C71) (SS9) CO) C
Molecular Formula
C30H28N6O6S4
Additionnal Information
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU (VAR) 3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR) .
Storage Conditions
2 years -80 in solvent
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