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Nutlin-3b

Product Specifications

CAS Number

675576-97-3

Synonyms

(+) -Nutlin-3

Target

MDM2/MDMX

Applications

Apoptosis

Smiles

CC (C) OC1=C (C=CC (=C1) OC) C2=NC (C (N2C (=O) N3CCNC (=O) C3) C4=CC=C (C=C4) Cl) C5=CC=C (C=C5) Cl

Molecular Formula

C30H30Cl2N4O4

Additionnal Information

Nutlin-3b ((+) -Nutlin-3) is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+) -enantiomer of Nutlin-3 as in comparison with opposite (-) -enantiomer Nutlin-3a.

Storage Conditions

2 years -80 in solvent

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