Nutlin-3b
Product Specifications
CAS Number
675576-97-3
Synonyms
(+) -Nutlin-3
Target
MDM2/MDMX
Applications
Apoptosis
Smiles
CC (C) OC1=C (C=CC (=C1) OC) C2=NC (C (N2C (=O) N3CCNC (=O) C3) C4=CC=C (C=C4) Cl) C5=CC=C (C=C5) Cl
Molecular Formula
C30H30Cl2N4O4
Additionnal Information
Nutlin-3b ((+) -Nutlin-3) is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+) -enantiomer of Nutlin-3 as in comparison with opposite (-) -enantiomer Nutlin-3a.
Storage Conditions
2 years -80 in solvent
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