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Macitentan

Product Specifications

CAS Number

441798-33-0

Synonyms

ACT 064992

Target

Endothelin Receptor

Applications

GPCR & G Protein

Smiles

CCCNS (=O) (=O) NC1=C (C (=NC=N1) OCCOC2=NC=C (C=N2) Br) C3=CC=C (C=C3) Br

Molecular Formula

C19H20Br2N6O4S

Additionnal Information

Macitentan is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM.

Storage Conditions

2 years -80 in solvent

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