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Tubastatin A

Product Specifications

CAS Number

1252003-15-8

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CN1CCC2=C (C1) C3=CC=CC=C3N2CC4=CC=C (C=C4) C (=O) NO

Molecular Formula

C20H21N3O2

Additionnal Information

Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold) . Tubastatin A promotes autophagy and increases apoptosis.

Storage Conditions

2 years -80 in solvent

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