KU-0060648
Product Specifications
CAS Number
881375-00-4
Target
DNA-PK
Applications
PI3K/Akt/mTOR
Smiles
CCN1CCN (CC1) CC (=O) NC2=C3C4=CC=CC=C4SC3=C (C=C2) C5=CC=CC6=C5OC (=CC6=O) N7CCOCC7
Molecular Formula
C33H34N4O4S
Additionnal Information
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
Storage Conditions
2 years -80 in solvent
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