GDC-0349
Product Specifications
CAS Number
1207360-89-1
Synonyms
RG-7603
Target
MTOR
Applications
PI3K/Akt/mTOR
Smiles
CCNC (=O) NC1=CC=C (C=C1) C2=NC3=C (CCN (C3) C4COC4) C (=N2) N5CCOCC5C
Molecular Formula
C24H32N6O3
Additionnal Information
GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
Storage Conditions
2 years -80 in solvent
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