Capivasertib (AZD5363)
Product Specifications
CAS Number
1143532-39-1
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
C1CN (CCC1 (C (=O) NC (CCO) C2=CC=C (C=C2) Cl) N) C3=NC=NC4=C3C=CN4
Molecular Formula
C21H25ClN6O2
Additionnal Information
Capivasertib (AZD5363) potently inhibits all isoforms of Akt (Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2. Phase 2.
Storage Conditions
2 years -80 in solvent
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