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Nirogacestat (PF-03084014)

Product Specifications

CAS Number

1290543-63-3

Synonyms

PF-3084014

Target

Apoptosis related

Applications

Apoptosis

Smiles

CCCC (C (=O) NC1=CN (C=N1) C (C) (C) CNCC (C) (C) C) NC2CCC3=C (C2) C (=CC (=C3) F) F

Molecular Formula

C27H41F2N5O

Additionnal Information

Nirogacestat (PF-03084014, PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM in a cell-free assay. Nirogacestat (PF-03084014, PF-3084014) induces apoptosis. Phase 2.

Storage Conditions

2 years -80 in solvent

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