Tenovin-1
Product Specifications
CAS Number
380315-80-0
Target
P53
Applications
Apoptosis
Smiles
CC (=O) NC1=CC=C (C=C1) NC (=S) NC (=O) C2=CC=C (C=C2) C (C) (C) C
Molecular Formula
C20H23N3O2S
Additionnal Information
Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also an inhibitor of dihydroorotate dehydrogenase (DHODH) .
Storage Conditions
2 years -80 in solvent
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