Plixorafenib (PLX8394)
Product Specifications
CAS Number
1393466-87-9
Target
Raf
Applications
MAPK
Smiles
C1CC1C2=NC=C (C=N2) C3=CC4=C (NC=C4C (=O) C5=C (C=CC (=C5F) NS (=O) (=O) N6CCC (C6) F) F) N=C3
Molecular Formula
C25H21F3N6O3S
Additionnal Information
Plixorafenib (PLX8394) is a next-generation, orally available, small-molecule BRAF inhibitor with IC50 values of 3.8 nM, 14 nM and 23 nM for BRAF (V600E), WT BRAF and CRAF respectively. It has potential antineoplastic activity.
Storage Conditions
3 years -20°C powder
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