Larotrectinib sulfate
Product Specifications
CAS Number
1223405-08-0
Synonyms
LOXO-101 sulfate, ARRY-470 sulfate
Target
Trk receptor
Applications
Protein Tyrosine Kinase
Smiles
C1CC (N (C1) C2=NC3=C (C=NN3C=C2) NC (=O) N4CCC (C4) O) C5=C (C=CC (=C5) F) F.OS (=O) (=O) O
Molecular Formula
C21H22F2N6O2.H2SO4
Additionnal Information
Larotrectinib sulfate is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK) . Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest.
Storage Conditions
2 years -80 in solvent
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