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SIS3 HCl

Product Specifications

CAS Number

521984-48-5

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CN1C (=C (C2=C1N=CC=C2) C=CC (=O) N3CCC4=CC (=C (C=C4C3) OC) OC) C5=CC=CC=C5.Cl

Molecular Formula

C28H27N3O3.HCl

Additionnal Information

SIS3, a novel specific inhibitor of Smad3, inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways.

Storage Conditions

2 years -80 in solvent

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