SIS3 HCl
Product Specifications
CAS Number
521984-48-5
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CN1C (=C (C2=C1N=CC=C2) C=CC (=O) N3CCC4=CC (=C (C=C4C3) OC) OC) C5=CC=CC=C5.Cl
Molecular Formula
C28H27N3O3.HCl
Additionnal Information
SIS3, a novel specific inhibitor of Smad3, inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways.
Storage Conditions
2 years -80 in solvent
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