Lifirafenib (BGB-283)
Product Specifications
CAS Number
1446090-79-4
Synonyms
Beigene-283
Target
Raf
Applications
MAPK
Smiles
C1CC (=O) NC2=NC=CC (=C21) OC3=CC4=C (C=C3) OC5C4C5C6=NC7=C (N6) C=C (C=C7) C (F) (F) F
Molecular Formula
C25H17F3N4O3
Additionnal Information
Lifirafenib (BGB-283, Beigene-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC472595-500 1x 500 µL
PAX5 / BSAP (Early B-Cell Marker) (PAX5/2595), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC683645-100 1x 100 µL
CD61 / Integrin '3 / Platelet Glycoprotein IIIa (Platelet Marker) (rITGB3/2145), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
E-UNEL-H0374-01 5x 96 Tests
Uncoated Human ACV-A (Activin A) ELISA Kit
Sign In for Pricing
View Details E-UNEL-H0374-02 15x 96 Tests
Uncoated Human ACV-A (Activin A) ELISA Kit
Sign In for Pricing
View Details 