Lifirafenib (BGB-283)
Product Specifications
CAS Number
1446090-79-4
Synonyms
Beigene-283
Target
Raf
Applications
MAPK
Smiles
C1CC (=O) NC2=NC=CC (=C21) OC3=CC4=C (C=C3) OC5C4C5C6=NC7=C (N6) C=C (C=C7) C (F) (F) F
Molecular Formula
C25H17F3N4O3
Additionnal Information
Lifirafenib (BGB-283, Beigene-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
R1356m 1 Each
Mouse Alox15b / Arachidonate 15-lipoxygenase B Recombinant Protein
Sign In for Pricing
View Details 
TL700081V 500 µL Each
Olr297 Rat shRNA Lentiviral Particle (Locus ID 293596)
Sign In for Pricing
View Details 
MBS7066537 Inquire
Recombinant Saccharomyces cerevisiae Autophagy-related protein 33 (ATG33), partial
Sign In for Pricing
View Details 
245964 100 µL
FANCC (Fanconi Anemia, Complementation Group C, FA3, FAC, FACC, FLJ14675)
Sign In for Pricing
View Details