Lifirafenib (BGB-283)
Product Specifications
CAS Number
1446090-79-4
Synonyms
Beigene-283
Target
Raf
Applications
MAPK
Smiles
C1CC (=O) NC2=NC=CC (=C21) OC3=CC4=C (C=C3) OC5C4C5C6=NC7=C (N6) C=C (C=C7) C (F) (F) F
Molecular Formula
C25H17F3N4O3
Additionnal Information
Lifirafenib (BGB-283, Beigene-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
AF4839-SP 25 µg
Human/Mouse/Rat CARD11/CARMA1 Affinity Purified PAb
Sign In for Pricing
View Details LV697191 1.0 µg DNA
RPS12 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
Sign In for Pricing
View Details