CHZ868
Product Specifications
CAS Number
1895895-38-1
Target
JAK
Applications
Angiogenesis
Molecular Formula
C22H19F2N5O2
Additionnal Information
CHZ868 is an inhibitor of type II JAK2 with an IC50 value of 0.17 μM in EPOR JAK2 WT Ba/F3 cells. CHZ868 demonstrates 60- to 70-fold higher inhibition of JAK1-/TYK2-mediated nuclear STAT1 translocation compared to pan-JAK inhibitors.
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