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Avadomide (CC-122)

Product Specifications

CAS Number

1015474-32-4

Target

E3 Ligase

Applications

Ubiquitin

Smiles

CC1=NC2=CC=CC (=C2C (=O) N1C3CCC (=O) NC3=O) N

Molecular Formula

C14H14N4O3

Additionnal Information

Avadomide (CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma (DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.

Storage Conditions

2 years -80 in solvent

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