What is the catalog number for NVP-CGM097?

The catalog number for NVP-CGM097 is C13018-100mg.

What sizes are available for NVP-CGM097?

NVP-CGM097 is available in the following size(s): 100 mg.

Is NVP-CGM097 in stock?

NVP-CGM097 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for NVP-CGM097?

NVP-CGM097 is requires dry ice shipping.

NVP-CGM097

Product Specifications

CAS Number

1313363-54-0

Synonyms

CGM-097

Target

MDM2/MDMX

Applications

Apoptosis

Smiles

CC (C) OC1=C (C=C2CC (=O) N (C (C2=C1) C3=CC=C (C=C3) Cl) C4=CC=C (C=C4) N (C) CC5CCC (CC5) N6CCN (C (=O) C6) C) OC

Molecular Formula

C38H47ClN4O4

Additionnal Information

NVP-CGM097 is a highly potent and selective MDM2 inhibitor with Ki value of 1.3 nM for hMDM2 in TR-FRET assay. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway.