SGI-7079
Product Specifications
CAS Number
1239875-86-5
Target
Axl
Applications
Protein Tyrosine Kinase
Smiles
CC1=CNC2=NC (=NC (=C12) C3=CC=CC (=C3) CC#N) NC4=CC (=C (C=C4) N5CCN (CC5) C) F
Molecular Formula
C26H26FN7
Additionnal Information
SGI-7079, a novel selective Axl inhibitor with an IC50 of 58 nM in vitro, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.
Storage Conditions
2 years -80 in solvent
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