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SGI-7079

Product Specifications

CAS Number

1239875-86-5

Target

Axl

Applications

Protein Tyrosine Kinase

Smiles

CC1=CNC2=NC (=NC (=C12) C3=CC=CC (=C3) CC#N) NC4=CC (=C (C=C4) N5CCN (CC5) C) F

Molecular Formula

C26H26FN7

Additionnal Information

SGI-7079, a novel selective Axl inhibitor with an IC50 of 58 nM in vitro, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.

Storage Conditions

2 years -80 in solvent

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