LY3009120

Product Specifications

CAS Number

1454682-72-4

Synonyms

DP-4978

Target

Raf

Applications

MAPK

Smiles

CC1=CC (=C (C=C1C2=C (N=C3C (=C2) C=NC (=N3) NC) C) NC (=O) NCCC (C) (C) C) F

Molecular Formula

C23H29FN6O

Additionnal Information

LY03009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. LY03009120 induces autophagy. Phase 1.

Storage Conditions

2 years -80 in solvent

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