OICR-9429
Product Specifications
CAS Number
1801787-56-3
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CN1CCN (CC1) C2=C (C=C (C=C2) C3=CC=CC (=C3) CN4CCOCC4) NC (=O) C5=CNC (=O) C=C5C (F) (F) F
Molecular Formula
C29H32F3N5O3
Additionnal Information
OICR-9429 is a potent antagonist of the interaction of WDR5 with peptide regions of MLL and Histone 3 and reduces viability of acute myeloid leukemia cells in vitro. It binds to WDR5 with high affinity (KD = 93 ± 28 nM.
Storage Conditions
2 years -80 in solvent
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