Tretazicar (CB1954)
Product Specifications
CAS Number
21919-05-1
Synonyms
NSC 115829
Target
DNA alkylator
Applications
DNA Damage/DNA Repair
Smiles
C1CN1C2=C (C=C (C (=C2) C (=O) N) [N+] (=O) [O-]) [N+] (=O) [O-]
Molecular Formula
C9H8N4O5
Additionnal Information
Tretazicar (CB1954) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD (P) H quinone oxidoreductase 2.
Storage Conditions
2 years -80 in solvent
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