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Tretazicar (CB1954)

Product Specifications

CAS Number

21919-05-1

Synonyms

NSC 115829

Target

DNA alkylator

Applications

DNA Damage/DNA Repair

Smiles

C1CN1C2=C (C=C (C (=C2) C (=O) N) [N+] (=O) [O-]) [N+] (=O) [O-]

Molecular Formula

C9H8N4O5

Additionnal Information

Tretazicar (CB1954) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD (P) H quinone oxidoreductase 2.

Storage Conditions

2 years -80 in solvent

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