Nazartinib (EGF816)
Product Specifications
CAS Number
1508250-71-2
Synonyms
NVS-816
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=NC=CC (=C1) C (=O) NC2=NC3=C (N2C4CCCCN (C4) C (=O) C=CCN (C) C) C (=CC=C3) Cl
Molecular Formula
C26H31ClN6O2
Additionnal Information
Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Storage Conditions
2 years -80 in solvent
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