A-1331852
Product Specifications
CAS Number
1430844-80-6
Target
Bcl-2
Applications
Apoptosis
Smiles
CC1=C (C=NN1CC23CC4CC (C2) CC (C4) C3) C5=C (N=C (C=C5) N6CCC7=C (C6) C (=CC=C7) C (=O) NC8=NC9=CC=CC=C9S8) C (=O) O
Molecular Formula
C38H38N6O3S
Additionnal Information
A-1331852 is a potent and selectiveBCL-XL inhibitor with Ki value less than 0.01 nM for BCL-XL and 6 nM, 4 nM, 142 nM for Bcl-2, Bcl-W, MCL-1 respectively. It may be useful in the treatment of cancer, immune and autoimmune diseases.
Storage Conditions
2 years -80 in solvent
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MID2, CT (MID2, FXY2, RNF60, TRIM1, Probable E3 ubiquitin-protein ligase MID2, Midin-2, Midline defect 2, Midline-2, RING finger protein 60, Tripartite motif-containing protein 1) (AP)
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