A-1155463 Dihydrochloride
Product Specifications
CAS Number
1235034-55-5 (free base)
Target
Bcl-2
Applications
Apoptosis
Smiles
CN (C) CC#CC1=CC (=C (C=C1) OCCCC2=C (N=C (S2) N3CCC4=C (C3) C (=CC=C4) C (=O) NC5=NC6=CC=CC=C6S5) C (=O) O) F
Molecular Formula
C35H34Cl2FN5O4S2
Additionnal Information
A-1155463 Dihydrochloride, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W (Ki=19 nM) and MCL-1 (Ki>440 nM) .
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
OR1095241-01 250 mg
1- (4- ((1-methylpiperidin-4-yl) oxy) phenyl) ethanone
Sign In for Pricing
View Details OR1095241-02 500 mg
1- (4- ((1-methylpiperidin-4-yl) oxy) phenyl) ethanone
Sign In for Pricing
View Details OR1095241-03 1 g
1- (4- ((1-methylpiperidin-4-yl) oxy) phenyl) ethanone
Sign In for Pricing
View Details 
MBS2074312-01 0.1 mL
PE-Linked Polyclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK)
Sign In for Pricing
View Details MBS2074312-02 0.2 mL
PE-Linked Polyclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK)
Sign In for Pricing
View Details MBS2074312-03 0.5 mL
PE-Linked Polyclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK)
Sign In for Pricing
View Details