A-1155463 Dihydrochloride
Product Specifications
CAS Number
1235034-55-5 (free base)
Target
Bcl-2
Applications
Apoptosis
Smiles
CN (C) CC#CC1=CC (=C (C=C1) OCCCC2=C (N=C (S2) N3CCC4=C (C3) C (=CC=C4) C (=O) NC5=NC6=CC=CC=C6S5) C (=O) O) F
Molecular Formula
C35H34Cl2FN5O4S2
Additionnal Information
A-1155463 Dihydrochloride, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W (Ki=19 nM) and MCL-1 (Ki>440 nM) .
Storage Conditions
2 years -80 in solvent
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