CDKI-73
Product Specifications
CAS Number
1421693-22-2
Target
CDK
Applications
Cell Cycle
Smiles
CC1=C (SC (=N1) NC) C2=NC (=NC=C2F) NC3=CC (=CC=C3) S (=O) (=O) N
Molecular Formula
C15H15FN6O2S2
Additionnal Information
CDKI-73 (LS-007) is a potent CDK inhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia.
Storage Conditions
3 years -20°C powder
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