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CDKI-73

Product Specifications

CAS Number

1421693-22-2

Target

CDK

Applications

Cell Cycle

Smiles

CC1=C (SC (=N1) NC) C2=NC (=NC=C2F) NC3=CC (=CC=C3) S (=O) (=O) N

Molecular Formula

C15H15FN6O2S2

Additionnal Information

CDKI-73 (LS-007) is a potent CDK inhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia.

Storage Conditions

3 years -20°C powder

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