Dovitinib (TKI258) Lactate monohydrate
Product Specifications
CAS Number
915769-50-5
Synonyms
CHIR258
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CC (C (=O) O) O.CN1CCN (CC1) C2=CC3=C (C=C2) N=C (N3) C4=C (C5=C (C=CC=C5F) NC4=O) N.O
Molecular Formula
C24H29FN6O5
Additionnal Information
Dovitinib (TKI258) Lactate monohydrate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
Storage Conditions
2 years -80 in solvent
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