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Gilteritinib (ASP2215)

Product Specifications

CAS Number

1254053-43-4

Target

FLT3

Applications

Protein Tyrosine Kinase

Smiles

CCC1=C (N=C (C (=N1) C (=O) N) NC2=CC (=C (C=C2) N3CCC (CC3) N4CCN (CC4) C) OC) NC5CCOCC5

Molecular Formula

C29H44N8O3

Additionnal Information

Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM) .

Storage Conditions

2 years -80 in solvent

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