Pluripotin (SC1)
Product Specifications
CAS Number
839707-37-8
Target
ERK
Applications
MAPK
Smiles
CC1=C (C=C (C=C1) NC (=O) C2=CC (=CC=C2) C (F) (F) F) N3CC4=CN=C (N=C4N (C3=O) C) NC5=CC (=NN5C) C
Molecular Formula
C27H25F3N8O2
Additionnal Information
Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal. Pluripotin also inhibits RSK1, RSK2, RSK3 and RSK4 with IC50 of 0.5 μM, 2.5 μM, 3.3 μM and 10.0 μM, respectively.
Storage Conditions
2 years -80 in solvent
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