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Ro-3306

Product Specifications

CAS Number

872573-93-8

Target

CDK

Applications

Cell Cycle

Smiles

C1=CC2=C (C=CC (=C2) C=C3C (=O) NC (=NCC4=CC=CS4) S3) N=C1

Molecular Formula

C18H13N3OS2

Additionnal Information

RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with Ki of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.

Storage Conditions

2 years -80 in solvent

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