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SCR7

Product Specifications

CAS Number

14892-97-8

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

C1=CC=C (C=C1) C2=NC3=C (NC (=S) NC3=O) N=C2C4=CC=CC=C4

Molecular Formula

C18H12N4OS

Additionnal Information

SCR7 is a specific DNA Ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ) . It increases the efficiency of HDR-mediated genome editing up to 19-fold using CRISPR/Cas9 in mammalian cells and mouse embryos.

Storage Conditions

2 years -80 in solvent

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