What is the catalog number for ML141?

The catalog number for ML141 is C12872-10mM/1mL.

What sizes are available for ML141?

ML141 is available in the following size(s): 10 mM/1mL.

ML141 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for ML141?

ML141 is requires dry ice shipping.

ML141

Product Specifications

CAS Number

71203-35-5

Synonyms

CID-2950007

Target

Rho

Applications

Cell Cycle

Smiles

COC1=CC=C (C=C1) C2CC (=NN2C3=CC=C (C=C3) S (=O) (=O) N) C4=CC=CC=C4

Molecular Formula

C22H21N3O3S

Additionnal Information

ML141 (CID-2950007) is demonstrated to be a potent, selective and reversible non-competitive inhibitor of Cdc42 GTPase suitable for in vitro assays, with IC50 of 200 nM and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7) . ML141 is associated with an increase in p38 activation and may induce p38-dependent apoptosis/senescence. ML141 also protects neuroblastoma cells from metformin-induced apoptosis.